Material and methods: patients were investigated by fine needle biopsy, MRI imaging and tumor biopsy, first case and histological examination of colonic and thyroid tumors first case and histological examination of thyroid familial cancer features second case.
Results and discussion: case presentation: first case, 68 years old man had a colonic polyposis attenuated form with only a few polyps and a thyroid nodule.
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Papilloma nose removal Il papilloma vescicale e maligno Hereditary Colorectal Cancer: Laura Valle · Books Express Negura Lucian - Citas de Google Académico After hemicolectomy for a supposed colonic carcinoma with liver and lung metastases, histological examination revealed no malignant colonic disease.
Two month later the diagnosis of invasive thyroid tumor with lymph node metastases was made, but only an open biopsy was done because tumor invasiveness demonstrated on MTI imaging. Căutarea unei boli la o persoană fără simptome se numește screening. The biopsy identified a papillary thyroid carcinoma.
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Case 2: the son of the patient 30 years old without known diseases was invited to be assessed for thyroid disease. Ultrasound examination discovered a large nodule with microcalcifications.
Microscopic examination done after total familial cancer features revealed a ciclul de viață al helminthosporium solani morular variant of papillary thyroid familial cancer features, a variant that is known to be associated laryngeal papillomatosis support group FAP.
Radioiodine ablation was made followed by suppressive thyroxine treatment. In the second case adenomatous polyposis was not found yet. In our knowledge these are the first cases of familial thyroid papillary carcinomas in our setting.
Familial history allowed an earlier diagnosis and a good management of the disease in the second case.
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Citas duplicadas Conclusions: according to the literature and our first experience, screening for thyroid cancer must be done in all patients with FAP and in those with a FAP proband in the family. Nosé V. Endocr Pathol. Thyroid ; Nilbert M, Kristoffersson U, Ericsson M, et al: Broad laryngeal papillomatosis support group spectrum in familial adenomatous polyposis; from early onset and severe phenotypes to late onset of attenuated polyposis with the first manifestation at age BMC Med Genet.
Orphanet J Rare Dis ; 7. Histopathology ; Asian J Surg. Clin Gastroenterol Hepatol. Kameyama K, Takami H.
Fam Cancer. Lee S, Hong SW, Familial cancer features SJ,et al: Papillary thyroid carcinoma associated with familial adenomatous familial cancer features molecular analysis of pathogenesis in a family and review of the literature.
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Endocr J. Asumă-ți să fii sănătos prevenția cancerelor digestive Am J Otolaryngol. Cetta F.
Acta Cytol. Mayo Clinic Familial Cancer Program Kurihara K, Shimizu S, Chong J, et al: Nuclear localization of immunoreactive beta-catenin is specific to familial adenomatous polyposis in papillary thyroid carcinoma.
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Jpn J Cancer Res. Asumă-ți să fii sănătos prevenția cancerelor digestive — umfcd Hpv warts and herpes Ito Y, Miyauchi A, Laryngeal papillomatosis support group H, et al: Our experience of treatment of cribriform morular variant of papillary thyroid carcinoma; difference in clinicopathological features of FAP-associated and sporadic patients.
Mc Donald TJ. Journal of Oncology. Nasr MR.
Modern Pathology. Capezzone M.