Chronic inflammation is involved in tumor development, tumor growth, progression and metastasis and, also, in resistance to therapy. As it is already acknowledged inflammatory bowel diseases IBD such as ulcerative colitis and Crohn disease are cancer colorectal has linked to an increased risk of colorectal cancer as high as 10 fold.
Various inflammatory cytokines have been studied as they facilitate the cancer colorectal has development.
P Abstract Introduction. Results from single medical centers having large numbers of patients with multiple colonic polyps that have undergone colonoscopy management are rare. Material and method. The present study is based on 2, cases enrolled during andincluding patients that underwent colonoscopy for various reasons in the Department for Upper and Lower Endoscopy of Witting Clinical Hospital, Bucharest, Romania.
Among those the most relevant are: C reactive protein, interleukin 6 and tumor necrosis factor alpha. The majority of published studies points toward a positive link between the increased serum level of those inflammatory molecules and the risk of colorectal cancer.
Future studies are needed to address the issue of novel oncological therapy that interfere with inflammatory mechanism of colorectal cancer. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy.
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